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March 24, 2026Sexually Transmitted Diseases

Clinical Characteristics and Trends of Lymphogranuloma Venereum Versus Non-LGV Chlamydia trachomatis Anorectal Infections: A Six-Year Retrospective Study

Loreto Sangorrin-Lapieza María Victoria Castaño-Amores David Rial-Crestelo María De Lagarde Otilia Bisbal Juan Martín-Torres Paula López-Roa

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Key Points

The aim is to compare clinical characteristics and trends of lymphogranuloma venereum (LGV) and non-LGV chlamydia infections over six years.
Conducted a six-year retrospective analysis of anorectal chlamydia infections.
Analyzed cases among high-risk populations, particularly men who have sex with men and individuals living with HIV.
Examined trends in testing and positivity rates for LGV and non-LGV infections.
Overall chlamydia positivity declined despite increased testing.
The proportion of LGV cases rose within high-risk groups.
LGV infections presented with more symptoms and co-infections, correlating with risky sexual behaviors.

Implication

This retrospective study compares clinical trends in LGV and non-LGV chlamydia infections in high-risk groups, suggesting an increase in LGV cases.

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Cite This Study

Sangorrin-Lapieza et al. (2026) studied this question.

synapsesocial.com/papers/69c4ccaffdc3bde4489180c5 https://doi.org/10.1097/olq.0000000000002295

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Observational study of anorectal Chlamydia trachomatis infections in France through the lymphogranuloma venereum surveillance network, 2010–2015Observational Study · 2018 · 15 citations
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