Key result
Elevated preoperative NT-proBNP and early ICU SOFA scores independently predict higher 6-month mortality after cardiac surgery.
Why the study?
Postoperative mortality after cardiac surgery remains a major challenge, and early identification of higher-risk patients could guide ICU monitoring strategies and resource allocation.
Do elevated preoperative NT-proBNP and early postoperative SOFA scores predict 6-month mortality in adult patients undergoing cardiac surgery?
Cohort (n=147)
No
Do elevated preoperative NT-proBNP and early postoperative SOFA scores predict 6-month mortality in adult patients undergoing cardiac surgery?
Effect estimate: HR 1.92 (95% CI 1.11-3.33)
Preoperative NT-proBNP >1800 pg/mL and a SOFA score ≥6 within 24 hours of ICU admission are strong, independent predictors of 6-month mortality after cardiac surgery, providing a practical framework for early risk stratification.
No takes yet. Share an insight, caveat, or question.
May warrant closer surveillance after cardiac surgery; extends prognostic utility of NT-proBNP and SOFA to 6-month mortality.
Cortés-Marín et al. (2026) conducted a cohort in Cardiac surgery (n=147). Preoperative NT-proBNP and early SOFA score was evaluated on 6-month mortality (HR 1.92, 95% CI 1.11-3.33). Preoperative NT-proBNP >1800 pg/mL and a SOFA score ≥6 within 24 hours of ICU admission independently predicted 6-month mortality after cardiac surgery (HR 1.92 and HR 5.31, respectively).
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