Findings show significant association between soluble SIGLEC1 levels and disease activity in idiopathic inflammatory myopathies, indicating its potential as a monitoring tool.
scSIGLEC1 levels are a promising biomarker for monitoring overall IIM disease activity, as well as activity involving the cutaneous, musculoskeletal, and gastrointestinal systems.
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Barreth et al. (2026) studied this question.
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