Comparative effectiveness study shows treatment discontinuation risk in adults with opioid use disorder, suggesting support is needed.
In this comparative effectiveness study of adults with OUD in a Canadian setting, treatment discontinuation was common. Compared with methadone, SROM was associated with a slightly higher risk of treatment discontinuation and lower adherence but similar mortality risk. The findings suggest either medication may be appropriate if measures are in place to support retention.
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Socias et al. (2026) studied this question.
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