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Findings demonstrate that adiponectin reduces inflammation and hyperproliferation in keratinocytes, indicating therapeutic potential for psoriasis.
Our findings suggest that APN inhibits keratinocyte hyperproliferation and suppresses inflammation in TNF-α-induced keratinocytes. Moreover, APN treatment attenuates IMQ-induced psoriatic dermatitis in mice, supporting its potential as a therapeutic approach for psoriasis.
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Zhang et al. (2026) studied this question.
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