A study demonstrates that decellularized dental pulp hydrogel supports endodontic regeneration, implying its potential for dental therapies.
This study demonstrated the significance of pDDPM-G in functional endodontic regeneration using an orthotopic canine model. It was found that the use of pDDPM-G was not only beneficial for root development but also facilitated pulp-like tissue morphogenesis, dentinogenesis, angiogenesis and neurogenesis, thereby reconstructing hierarchically distributed functional pulp-dentine complexes.
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Liang et al. (2026) studied this question.
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