FOS Knockdown Alleviates Helicobacter pylori ‐Infected Gastritis by Suppressing Mast Cell Activation and Treg Polarization

Key Points

• This research aims to evaluate the effects of FOS silencing on mast cell activation and Treg polarization in Helicobacter pylori-induced gastritis.
• Conducted experiments on cells involved in HP-induced gastritis.
• Utilized FOS knockdown techniques to inhibit specific cell functions.
• Measured levels of mast cell activation and Treg polarization.
• FOS silencing significantly reduced mast cell activation.
• FOS knockdown led to decreased Treg cell polarization.
• Findings suggest a potential pathway for therapeutic intervention in HP-induced gastritis.