PulseTrendingJournal ClubResearchersJournalsExplore
Instagram
HomeTrendingJournal ClubExplore
Synapse
⌘+K
Synapse
March 26, 2026RespirologyOpen Access

OSA Endotyping as Targets for Treatment. How Far Have We Come?

View Full Paper
Ask AI
Bookmark
Share

Authors

WMW.T. McNicholasSBSara Op de BeeckPTPasquale Tondo

Discussion

Loading...

Member takes

Overview

Endotyping reveals alternative therapies for obstructive sleep apnoea, suggesting a shift from CPAP for less severe cases.

Key Points

  • The aim is to explore how endotyping in obstructive sleep apnoea can inform treatment options beyond CPAP.
  • Reviewed endotypes of obstructive sleep apnoea and their relevance to treatment options.
  • Examined current non-CPAP therapies including oral appliances and pharmacotherapy.
  • Analyzed reports on identifying endotypic factors that influence treatment decisions.
  • Continued dominance of CPAP for moderate and severe cases of obstructive sleep apnoea.
  • Recognition of multiple endotypes that suggest alternative therapies for less severe cases.
  • Effective pharmacotherapies have been developed targeting specific non-anatomical endotypes.

Cite This Study

McNicholas et al. (2026) studied this question.

synapsesocial.com/papers/69c4cddcfdc3bde44891ab21https://doi.org/10.1002/resp.70233
View Full Paper
Ask AI
Bookmark
Share