Giant interventricular septal hematoma is a potential complication of left bundle branch pacing that can be successfully managed with conservative medical therapy.
May signal need for post-discharge monitoring after LBBP; hypothesis-generating and should not yet change practice.
An 88-year-old woman underwent atrioventricular node ablation and left bundle branch pacing for atrial fibrillation. She presented to the emergency room several hours after discharge with dyspnea. An echocardiogram revealed a giant interventricular septal hematoma. The patient was successfully treated with conservative medical therapy, with eventual complete resolution of the hematoma. (Level of Difficulty: Intermediate.).
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Trivedi et al. (2023) studied this question.
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