Why the study?
Does chronic antiplatelet therapy impact infarct size and bleeding risk in patients with acute myocardial infarction?
Does chronic antiplatelet therapy impact infarct size and bleeding risk in patients with acute myocardial infarction?
Chronic antiplatelet therapy prior to AMI is unexpectedly associated with smaller infarct size without an increased adjusted bleeding risk.
Chronic APT linked to smaller AMI infarct size without excess bleeding; hypothesis-generating, requires randomized confirmation before practice change.
In patients with AMI, chronic APT is associated with higher baseline ischemic and bleeding risks. Despite this and unexpectedly, they have a smaller infarct size and similar adjusted bleeding risk.
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Campodonico et al. (2018) studied this question.
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