Do women with hypertrophic cardiomyopathy have worse survival and clinical presentation compared to men?
Women with hypertrophic cardiomyopathy have worse survival and present with more advanced disease than men, highlighting the need for potentially more aggressive diagnostic and therapeutic approaches.
Women with HCM present at more advanced age, with more symptoms, worse cardiopulmonary exercise tolerance, and different haemodynamics than men. Sex is an important determinant in HCM management as women with HCM have worse survival. Women may require more aggressive diagnostic and therapeutic approaches.
Geske et al. (Mon,) studied this question.