Bioinspired photoenzymatic cascade enabled by a bifunctional arylformamidase for efficient synthesis of L-kynurenine derivatives

Key Points

• The aim is to develop a more efficient method for synthesizing L-kynurenine derivatives through a bioinspired enzymatic approach.
• Utilized a bifunctional arylformamidase for catalysis
• Developed a photoenzymatic cascade process
• Compared efficiency against traditional synthetic methods
• Improved step economy in the synthesis of L-kynurenine derivatives
• Increased yield of desired products compared to conventional techniques
• Demonstrated versatility in producing various bioactive compounds