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March 27, 2026Clinical Cardiology2 citationsOpen Access

Voluntary Slow Breathing Exercise on Cardiovascular Parameters in Patients With Hypertension: A Systematic Review and Meta‐Analysis

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SCShenTing ChengYCYan ChenMYMan Yu

Key Result

Voluntary slow breathing exercise significantly reduced systolic blood pressure (MD -7.68), diastolic blood pressure (MD -4.02), and heart rate (MD -1.15) in patients with hypertension.

Key Points

  • To assess the effects of voluntary slow breathing exercise on cardiovascular parameters in hypertensive individuals.
  • Conducted a systematic review and meta-analysis per PRISMA guidelines.
  • Performed literature searches in PubMed, Web of Science, Embase, and the Cochrane Library.
  • Calculated mean differences and confidence intervals using RevMan 5.4 software.
  • Used fixed-effects or random-effects models based on heterogeneity tests.
  • Thirteen studies met inclusion criteria for analysis.
  • Voluntary slow breathing exercise significantly reduced systolic blood pressure (MD = -7.68; p < 0.001).
  • There was a significant decrease in diastolic blood pressure (MD = -4.02; p < 0.001).
  • Heart rate was significantly lower post-exercise (MD = -1.15; p < 0.001).
  • Improved autonomic modulation indicated by reduced LF/HF ratio (MD = -1.09; p = 0.01).

Structured PICO

Does voluntary slow breathing exercise reduce blood pressure and heart rate in patients with hypertension?

P
Population
Individuals with hypertension (pooled from 13 studies)
I
Intervention
Voluntary slow breathing exercise
C
Comparator
Control conditions
O
Outcome
Cardiovascular parameters including systolic blood pressure, diastolic blood pressure, and heart ratesurrogate

Voluntary slow breathing exercise is an effective non-pharmacological adjunct that significantly reduces systolic and diastolic blood pressure in patients with hypertension.

Abstract

ABSTRACT Background Non‐pharmacological interventions are increasingly recognized as complementary approaches in the management of hypertension. Among various non‐pharmacological interventions, voluntary slow breathing exercise has been proposed as a simple and accessible approach, but its comprehensive effects on cardiovascular parameters in hypertensive patients remain to be systematically summarized. Aim This systematic review and meta‐analysis aims to quantitatively assess the effects of voluntary slow breathing exercise on cardiovascular parameters in individuals with hypertension. Methods Following the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines, we conducted literature searches in four major databases (PubMed, Web of Science, Embase, and the Cochrane Library) to identify eligible studies. Meta‐analysis was conducted using RevMan 5.4 software. Effect sizes were pooled by calculating mean differences (MDs) and their 95% confidence intervals (CIs). A fixed‐effects or random‐effects model was used according to the results of the heterogeneity test. Results A total of thirteen studies met the predefined inclusion criteria. The pooled analysis demonstrated that voluntary slow breathing exercise significantly reduced systolic blood pressure (MD = −7.68; 95% CI: −9.87, −5.49; p < 0.001), diastolic blood pressure (MD = −4.02; 95% CI: −5.44, −2.60; p < 0.001), and heart rate (MD = −1.15; 95% CI: −1.73, −0.56; p < 0.001) compared to control conditions. Additionally, a significant reduction in the low‐frequency to high‐frequency power ratio (LF/HF) was observed (MD = −1.09; 95% CI: −1.94, −0.23; p = 0.01), indicating improved autonomic modulation. Conclusion Voluntary slow breathing exercise appears to be an effective adjuvant non‐pharmacological intervention for improving cardiovascular function, particularly in reducing blood pressure and heart rate, in patients with hypertension. These findings support its potential integration into hypertension management strategies.

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Cite This Study

Cheng et al. (2026) studied this question. Voluntary slow breathing exercise significantly reduced systolic blood pressure (MD -7.68), diastolic blood pressure (MD -4.02), and heart rate (MD -1.15) in patients with hypertension.

synapsesocial.com/papers/69c6204c15a0a509bde18b1ehttps://doi.org/10.1002/clc.70279
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