What question did this study set out to answer?

This study aims to evaluate the outcomes of elderly high-risk prostate cancer patients treated with prostate-only radiotherapy and androgen deprivation therapy.

March 27, 2026Journal of Personalized MedicineOpen Access

Omitting Elective Pelvic Nodes Irradiation in High Risk Prostate Cancer: Report on 43 Consecutive Elderly Patients

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Authors

ECEmanuele ChioccolaFederico II University Hospital MCMARA CAROPRESEFederico II University Hospital CGChristina Amanda GoodyearFederico II University Hospital

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Implication

Research reports excellent disease control with pelvic-only radiotherapy in high-risk elderly prostate cancer patients, suggesting a treatment de-escalation approach.

Key Points

This study aims to evaluate the outcomes of elderly high-risk prostate cancer patients treated with prostate-only radiotherapy and androgen deprivation therapy.
Conducted a retrospective review of 43 elderly patients with high-risk prostate cancer.
All patients received prostate-only radiotherapy and were staged with MRI, CT, or PET/CT.
Oncological endpoints included biochemical failure-free survival, disease-free survival, metastasis-free survival, and prostate cancer-specific survival.
100% of patients achieved biochemical failure-free survival at 5 and 7 years.
94.7% and 71.8% disease-free survival at 5 and 7 years, respectively.
Estimated metastasis-free survival of 97.6% at 5 years and 88.7% at 7 years.

Cite This Study

Chioccola et al. (2026) studied this question.

synapsesocial.com/papers/69c6209315a0a509bde19216 https://doi.org/10.3390/jpm16040177

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Implication

Research reports excellent disease control with pelvic-only radiotherapy in high-risk elderly prostate cancer patients, suggesting a treatment de-escalation approach.

Omitting Elective Pelvic Nodes Irradiation in High Risk Prostate Cancer: Report on 43 Consecutive Elderly Patients

Discussion

Member takes

Implication

Key Points

Cite This Study

Omitting Elective Pelvic Nodes Irradiation in High Risk Prostate Cancer: Report on 43 Consecutive Elderly Patients

Discussion

Member takes

Implication

Key Points

Cite This Study

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