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March 27, 2026Protein ScienceOpen Access

The complexities of respiratory chain biogenesis and maintenance in yeast mitochondria

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Authors

ACAndreas CarlströmCVCarmela Vazquez‐CalvoMOMartin Ott

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Overview

This review uncovers mechanisms of respiratory chain biogenesis in yeast mitochondria, suggesting complex interdependencies between genetic systems.

Key Points

  • This work aims to understand the biogenesis and maintenance mechanisms of respiratory chain complexes in yeast mitochondria.
  • Focus on respiratory chain complex III as a case study
  • Discuss coordination between nuclear gene expression and mitochondrial DNA-protein synthesis
  • Analyze recent data from baker's yeast to illustrate findings
  • Identified intricate biogenesis mechanisms for respiratory chain complexes
  • Highlighted dual genetic systems' cooperation for complex assembly
  • Revealed physical separation of biogenesis and function within mitochondria

Cite This Study

Carlström et al. (2026) studied this question.

synapsesocial.com/papers/69c620be15a0a509bde194e3https://doi.org/10.1002/pro.70545
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