Wcn26-8089 Efficacy and Safety of Telitacicept in Primary Immunoglobulin a Nephropathy Patients With Severely Impaired Renal Function

Conclusion: Scleroderma renal crisis (SRC) is a rare complication of systemic sclerosis, more frequent in the diffuse form, which can rapidly progress to acute kidney injury, need for renal replacement therapy, and death.Timely diagnosis requires clinical correlation with systemic sclerosis, exclusion of other thrombotic microangiopathies, and, when feasible, histological confirmation via renal biopsy.Early initiation of ACE inhibitors, particularly captopril, improves shortterm survival but does not guarantee renal recovery in all cases, highlighting the clinical heterogeneity and the need for predictive biomarkers and more effective therapeutic strategies.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.