Retrospective cohort study shows improvement in symptoms for men with LUTS, indicating potential benefits of combination therapy.
In men with mixed LUTS and prominent storage symptoms, tadalafil plus mirabegron was associated with improvement in overall symptom burden, bladder diary measures, and erectile-function scores without an obvious retention signal. The clinical benefit was clearer for IPSS than for OABSS, so early reassessment is important to identify men who do not improve.
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İnkaya et al. (2026) studied this question.
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