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The aim is to develop a simple and reliable ATR-FTIR method for quantitative analysis of acetaminophen in Panadol tablets.

ATR-FTIR Experiment for Instrumental Analysis Laboratory

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The aim is to develop a simple and reliable ATR-FTIR method for quantitative analysis of acetaminophen in Panadol tablets.
Conduct ATR-FTIR measurements of acetaminophen peak area between 1495 and 1530 cm–1.
Establish calibration curves for quantitative analysis.
Evaluate method ruggedness and reliability over a one-year period.
Achieved a relative error of determination of less than 4%.
Determined limit of detection (LOD) at 5.2 mg/mL and limit of quantification (LOQ) at 17.3 mg/mL.
Demonstrated low waste generation and feasibility for undergraduate laboratories.

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Experimental analysis reveals effective quantitative measurement of acetaminophen in tablets, indicating a reliable technique for education.

Santiago-Huertas et al. (2020) studied this question.

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Experimental analysis reveals effective quantitative measurement of acetaminophen in tablets, indicating a reliable technique for education.