What question did this study set out to answer?

This review aims to explore the relationship between fabrication techniques for nanogaps and their applications in biosensing using SERS and SEF.

March 28, 2026Nanoscale Advances0 citationsOpen Access

Review. SERS and SEF with enhancement in nanogaps: from fabrication to biosensing

ASAlisher SultangaziyevIBM (United States)DADinmukhamed AliyevNazarbayev University ASAnsar SeitkaliNazarbayev University

Key Points

This review aims to explore the relationship between fabrication techniques for nanogaps and their applications in biosensing using SERS and SEF.
Survey of existing literature on SERS and SEF spectroscopies
Analysis of nanogap fabrication techniques
Examination of biosensing applications utilizing enhanced nanogaps
Identified key fabrication methods that improve nanogap sensitivity
Discussed various biosensing applications benefiting from SERS and SEF enhancements
Supported correlation between nanogap characteristics and improved sensing performance

Abstract

This review surveys SERS and SEF spectroscopies, with a spotlight on the correlation between nanogap fabrication techniques and subsequent applications of those nanogaps in biosensing. In the last several decades,...

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