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March 28, 2026JAMA Ophthalmology5 citations

Discontinuation Approach and Follow-Up of Low-Concentration Atropine for Myopia Progression

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YZYuzhou ZhangXZXiu Juan ZhangEZEbenezer Zaabaar

Key Points

  • The aim is to assess the effects of tapering low-concentration atropine on myopia progression in children.
  • Participants divided into taper and stop groups
  • Follow-up over a 3-year period
  • Comparison based on degree of myopia at baseline
  • Taper group showed less myopia progression than the stop group
  • Difference was especially notable in younger children with higher myopia
  • Clinical significance of a 0.25-D difference remains unclear

Abstract

This study found that over 3 years, the participants in the taper group had less myopia progression than the stop group, particularly in children who were younger and had more myopia. However, to our knowledge, the clinical relevance of this approximately 0.25-D difference between treatment groups is not well understood from the current medical literature.

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Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/69c772058bbfbc51511e2287https://doi.org/10.1001/jamaophthalmol.2026.0436
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