Timing of Antithrombotic Initiation and Risk of Reocclusion After Mechanical Thrombectomy

Joanna M. Roy; Marissa Tucci; Basel Musmar; Michael P. Baldassari; Victor Gabriel El-Hajj; Rithvik Kata; Saman Sizdahkhani; E Atallah; Bachar El-Baba; Mary Penckofer; Jonathan A. Grossberg; Jane Khalife; Thana Theofanis; Preethi Ramchand; Richard F. Schmidt; Larami Mackenzie; Ritam Ghosh; Osman Kozak; Hekmat Zarzour; S Tjoumakaris; M. Reid Gooch; Robert H. Rosenwasser; Pascal M. Jabbour

doi:10.1227/neu.0000000000004013

Key Points

This research investigates the optimal timing for starting antithrombotic therapy following mechanical thrombectomy to reduce the risk of reocclusion.
Analyzed the timing of antithrombotic therapy initiation after mechanical thrombectomy.
Compared reocclusion rates based on therapy initiation timing, specifically within 24 hours, 1 to 7 days, and beyond 7 days.
Antithrombotic therapy initiated within 1 to 7 days significantly reduced reocclusion risk.
Starting therapy within 24 hours also provided protective benefits.
No protective effect was observed when therapy was initiated beyond 7 days.

Implication

Early initiation of antithrombotic therapy reduces reocclusion risk in patients after mechanical thrombectomy, suggesting timing is crucial.

Abstract

Early initiation of antithrombotic therapy after MT is protective against reocclusion, with the greatest benefit seen when started within 1 to 7 days, followed by within 24 hours. Initiation beyond 7 days was not protective against developing reocclusion.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Roy et al. (2026) studied this question.

synapsesocial.com/papers/69c772158bbfbc51511e2440 https://doi.org/10.1227/neu.0000000000004013

View at Publisher

Ask AI

Bookmark

Share

Timing of Antithrombotic Initiation and Risk of Reocclusion After Mechanical Thrombectomy

Key Points

Implication

Abstract

Discussion

Cite This Study

Timing of Antithrombotic Initiation and Risk of Reocclusion After Mechanical Thrombectomy

Key Points

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading