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This research examines the relative impacts of door-to-reperfusion time and onset-to-door time on patient outcomes in mechanical thrombectomy for acute ischemic stroke.

February 2, 2026Stroke

Abstract TP002: Door-to-Reperfusion Time Is More Strongly Associated with Poor Outcomes Than Onset-to-Door Time in Mechanical Thrombectomy for Acute Ischemic Stroke

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Authors

HSHideyuki ShimizuJikei University School of Medicine KSKenichi SakutaJikei University School of Medicine MOMotohiro OkumuraJikei University School of Medicine

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Implication

Analysis reveals door-to-reperfusion time affects outcomes in acute ischemic stroke, suggesting workflow improvements could help.

Key Points

This research examines the relative impacts of door-to-reperfusion time and onset-to-door time on patient outcomes in mechanical thrombectomy for acute ischemic stroke.
Analyzed data from a prospectively maintained registry of 1,984 stroke patients admitted between Jan 2018 and Oct 2024.
Included only patients who underwent mechanical thrombectomy and had accurate time data.
Categorized patients by modified Rankin Scale scores at 90 days to assess good and poor outcomes.
Calculated odds ratios for poor outcomes based on delays in onset-to-door and door-to-reperfusion times.
Out of 138 patients analyzed, 46 (33.3%) experienced poor outcomes at 90 days.
No significant difference in onset-to-door time between good and poor outcome groups (p = 0.186).
Door-to-reperfusion time was significantly longer in the poor outcome group (p = 0.013).
Each 30-minute delay in door-to-reperfusion time increased the odds of poor outcome by 9.4%, while onset-to-door time had a negligible effect.

Cite This Study

Shimizu et al. (2026) studied this question.

synapsesocial.com/papers/6980fc17c1c9540dea80def3 https://doi.org/10.1161/str.57.suppl_1.tp002

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Abstract TP002: Door-to-Reperfusion Time Is More Strongly Associated with Poor Outcomes Than Onset-to-Door Time in Mechanical Thrombectomy for Acute Ischemic Stroke

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Implication

Key Points

Cite This Study

Abstract TP002: Door-to-Reperfusion Time Is More Strongly Associated with Poor Outcomes Than Onset-to-Door Time in Mechanical Thrombectomy for Acute Ischemic Stroke

Discussion

Member takes

Implication

Key Points

Cite This Study

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