What question did this study set out to answer?

The study aims to investigate the link between the time from last known well to thrombectomy and patient outcomes after stroke.

February 2, 2026Stroke

Abstract DP276: Association Between Time to Thrombectomy and Functional Outcomes Up To 24 Hours After Last Known Well

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Authors

SZSonya ZhouUniversity of Pennsylvania MMMichael T. MullenTemple University LSLee SchwammYale University

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Implication

This observational study examines how time to thrombectomy affects outcomes in acute stroke with large vessel occlusion, suggesting urgency in treatment.

Key Points

The study aims to investigate the link between the time from last known well to thrombectomy and patient outcomes after stroke.
Analyzed data from the American Heart Association/American Stroke Association registry.
Included patients who underwent thrombectomy for anterior circulation large vessel occlusions.
Measured onset to arterial puncture times and their impact on functional outcomes at discharge.
Utilized generalized estimating equations for statistical analysis.
41,736 patients were included, with outcomes declining linearly as time to thrombectomy increased.
Each hour of delay decreased the odds of functional independence by 5.0%.
Patients with witnessed onset experienced a greater decrease in outcomes compared to those with unwitnessed onset.
Independent ambulation decreased by 4.2% for each hour delay, with stronger effects noted in patients with witnessed symptoms.

Cite This Study

Zhou et al. (2026) studied this question.

synapsesocial.com/papers/6980fd3cc1c9540dea80ef8c https://doi.org/10.1161/str.57.suppl_1.dp276

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Implication

This observational study examines how time to thrombectomy affects outcomes in acute stroke with large vessel occlusion, suggesting urgency in treatment.

Abstract DP276: Association Between Time to Thrombectomy and Functional Outcomes Up To 24 Hours After Last Known Well

Discussion

Member takes

Implication

Key Points

Cite This Study

Abstract DP276: Association Between Time to Thrombectomy and Functional Outcomes Up To 24 Hours After Last Known Well

Discussion

Member takes

Implication

Key Points

Cite This Study

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