Key result
EVT maintains benefit up to 24 hours, but in-hospital delays link to worse functional outcomes.
Why the study?
Does endovascular thrombectomy improve degree of disability at 90 days in patients with large vessel occlusion strokes presenting in the 6-24 hour window?
Population
Patients with large vessel occlusion strokes presenting in the extended window, selected using advanced…
Design
Meta-analysis
Follow-up
90 days
Authors
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The benefit of endovascular thrombectomy is preserved in the 6-24 hour window for LVO stroke when using advanced imaging selection, though minimizing in-hospital delays remains critical for optimal outcomes.
Meta-Analysis
Yes
Does endovascular thrombectomy improve degree of disability at 90 days in patients with large vessel occlusion strokes presenting in the 6-24 hour window?
p-value: p=0.038
The benefit of endovascular thrombectomy is preserved in the 6-24 hour window for LVO stroke when using advanced imaging selection, though minimizing in-hospital delays remains critical for optimal outcomes.
Nogueira et al. (2026) conducted a meta-analysis in Large vessel occlusion (LVO) stroke. Endovascular thrombectomy (EVT) was evaluated on Degree of disability at 90 days (modified Rankin Scale [mRS] 0-6) (p=0.038). Endovascular thrombectomy benefit is preserved across the 6-24-hour window with advanced imaging selection, but longer in-hospital delays were strongly associated with worse outcomes (P=0.038).
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