Comparative clinical evaluation of microfilled and nanofilled resin-based fissure sealants: A randomized controlled trial

Key Points

• The aim is to compare the clinical effectiveness of microfilled and nanofilled resin-based fissure sealants in children.
• Split-mouth randomized controlled trial design
• Involved 100 healthy children aged 6–12 years
• Groups were treated with either microfilled or nanofilled sealants
• Evaluation at 3 and 6 months using modified USPHS criteria
• Both sealant materials were found to be clinically effective
• Significant efficacy of both materials was observed at the 6-month follow-up