Inner Ear Schwannomas as a Risk Factor for Early Hearing Loss Independent of Vestibular Schwannoma Growth in NF2-related Schwannomatosis

Marina Brimioulle; Pieter Pretorius; Nathaniel McHugh; Joel Ward; Rajeev Mathew; Alexandros Boukas; Dorothy Halliday; Allyson Parry; Samuel MacKeith

doi:10.1097/mao.0000000000004879

March 26, 2026Otology & Neurotology

Inner Ear Schwannomas as a Risk Factor for Early Hearing Loss Independent of Vestibular Schwannoma Growth in NF2-related Schwannomatosis

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Key Points

The study aims to investigate the relationship between inner ear schwannomas and early hearing loss in NF2-related schwannomatosis.
Analyzed hearing loss data in patients with inner ear schwannomas and vestibular schwannomas
Compared age of hearing loss onset between patients with both tumors and those with vestibular schwannomas alone
Examined tumor size in relation to hearing decline
Patients with both inner ear schwannomas and vestibular schwannomas experienced hearing loss at younger ages
Hearing loss occurred with smaller vestibular schwannoma sizes in patients with inner ear schwannomas than those with vestibular schwannomas alone
These findings support the need for early intervention in affected patients

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Implication

Reveals early hearing loss in patients with both inner ear and vestibular schwannomas, suggesting timely interventions are needed.

Abstract

IES is associated with earlier hearing loss, particularly with respect to loss of serviceable hearing. These findings suggest that patients with both a VS and an IES may experience hearing decline at younger ages and at smaller VS sizes than those with VS alone. This information may inform clinical decision-making and guide timing of interventions in NF2-SWN.

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Brimioulle et al. (2026) studied this question.

synapsesocial.com/papers/69c7722a8bbfbc51511e2630 https://doi.org/10.1097/mao.0000000000004879

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Inner Ear Schwannomas as a Risk Factor for Early Hearing Loss Independent of Vestibular Schwannoma Growth in NF2-related Schwannomatosis

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Inner Ear Schwannomas as a Risk Factor for Early Hearing Loss Independent of Vestibular Schwannoma Growth in NF2-related Schwannomatosis

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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