An advanced organic chemistry lab demonstrates chiral oxazoline synthesis, suggesting practical research experience for students.
An advanced organic chemistry laboratory for undergraduate students is described. The multistep synthesis is broken down into two parts. The overall four-step reaction sequence starts with L-valine and ends with a chiral aromatic oxazoline maintaining the integrity of the chiral amino acid. This is intended to be a “research-type” laboratory experience to introduce students to the process of conducting research.
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Wyatt et al. (2006) studied this question.
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