Delonix regia extract attenuates diabetic left ventricular remodeling by modulating eNOS/NO/cGMP and NF-κB/iNOS/TNF-α pathways alongside anti-apoptotic and antifibrotic actions.
Does methanolic extract of Delonix regia flower attenuate left ventricular remodeling in diabetic cardiomyopathy?
Delonix regia flower extract shows preclinical potential in attenuating diabetic cardiac remodeling through anti-apoptotic, antifibrotic, and specific signaling pathway modulations.
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Methanolic extract of D. regia may have therapeutic potential in the attenuating left ventricular remodeling associated with diabetic cardiomyopathy. These effects appear to be associated with modulation of eNOS/NO/cGMP and NF-κB/iNOS/TNF-α trajectories, along with anti-apoptotic and antifibrotic actions.
Hassan et al. (Sun,) reported a other. Delonix regia extract attenuates diabetic left ventricular remodeling by modulating eNOS/NO/cGMP and NF-κB/iNOS/TNF-α pathways alongside anti-apoptotic and antifibrotic actions.