Experiment synthesizes ruthenium phosphine catalysts to convert alcohols into ketones, highlighting practical chemistry skills.
This experiment might be part of a senior organometallic course. It requires the synthesis and characterization of several ruthenium phosphine complexes, and their subsequent use for catalyzing the conversion of 1-phenylethanol to acetophenone and back. The design of the experiment encourages some choices to be made by the student, although the initial syntheses are recipe-driven. Bench techniques required include working under an inert atmosphere, reflux, distillation, and chromatography. NMR and IR spectroscopy are used for characterization.
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Berry et al. (2003) studied this question.
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