The Saccharomyces cerevisiae factory-driven efficient glucaric acid production: from metabolic engineering to process optimization

Zijuan Wu; Yan An; Wenjun Sun; Chenglun Tang; Tianpeng Chen; Yong Chen

doi:10.1039/d6re00053c

January 1, 2026Reaction Chemistry & Engineering

The Saccharomyces cerevisiae factory-driven efficient glucaric acid production: from metabolic engineering to process optimization

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Key Points

The aim is to enhance glucaric acid production from Saccharomyces cerevisiae through metabolic engineering and optimization techniques.
Employed metabolic engineering strategies to enhance biosynthetic pathways.
Implemented process optimization for higher yield and efficiency.
Utilized renewable resources as feedstock for production.
Achieved significant increases in glucaric acid yield compared to previous methods.
Demonstrated the feasibility of using renewable resources in production processes.

Implication

Demonstrates optimized glucaric acid production in Saccharomyces cerevisiae, suggesting potential for green chemical applications.

Abstract

Glucaric acid, a high-value platform compound derived from renewable resources, has garnered increasing attention due to its broad applications in food additives, pharmaceutical precursors, and green chemical industries. Compared to...

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Cite This Study

Wu et al. (2026) studied this question.

synapsesocial.com/papers/69c8c247de0f0f753b39c8fe https://doi.org/10.1039/d6re00053c

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The Saccharomyces cerevisiae factory-driven efficient glucaric acid production: from metabolic engineering to process optimization

Key Points

Implication

Abstract

Discussion

Cite This Study

The Saccharomyces cerevisiae factory-driven efficient glucaric acid production: from metabolic engineering to process optimization

Key Points

Implication

Abstract

Discussion

Cite This Study

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