What question did this study set out to answer?

The aim is to understand the factors contributing to treatment failure among individuals on second-line ART for HIV in Zambia.

March 29, 2026International Health0 citationsOpen Access

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Treatment failure and associated factors among people living with HIV on second-line antiretroviral therapy in Zambia

KSKaziwe SikambaleUniversity of Lusaka CCChitalu ChandaMinistry of Health VDVictor DakaNorthrise University

Key Points

The aim is to understand the factors contributing to treatment failure among individuals on second-line ART for HIV in Zambia.
Conducted an observational study focusing on individuals on second-line antiretroviral therapy (ART) in Zambia.
Analyzed the impact of routine viral load monitoring on treatment outcomes.
Assessed adherence support initiatives for improving ART efficacy.
Identified a significant rate of treatment failure among individuals on second-line ART.
Highlighted the necessity for enhanced viral load monitoring.
Emphasized the importance of adherence support for better treatment outcomes.

Abstract

This study found that treatment failure among people living with HIV on second-line ART in Zambia remains a significant concern. To improve treatment outcomes and reduce HIV-associated morbidity and mortality in Zambia, strengthening routine viral load monitoring and adherence support initiatives is essential.

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Cite This Study

Sikambale et al. (Fri,) studied this question.

synapsesocial.com/papers/69c8c277de0f0f753b39cbd2 https://doi.org/https://doi.org/10.1093/inthealth/ihag024

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