What question did this study set out to answer?

The aim is to explore the production of erbium-165 through alpha particle-induced reactions on holmium targets.

March 29, 2026Open Access

Measurement of excitation functions of the alpha particle-induced nuclear reactions up to 50 MeV on holmium target

Key Points

The aim is to explore the production of erbium-165 through alpha particle-induced reactions on holmium targets.
Irradiated holmium foils with a 50 MeV alpha beam.
Used the activation method and stacked target technique.
Determined cross sections for producing multiple thulium isotopes.
Measured cross sections for the 165 Ho(α,4n) 165 Tm reaction.
Investigated production across various thulium isotopes (165, 166, 167, 168 Tm).
Findings indicate effective production methods for therapeutic radionuclides.

Abstract

Abstract 165 Er is a pure Auger-electron emitter that shows great potential for therapeutic applications in nuclear medicine. Various production methods have been described in the literature, typically involving the irradiation of erbium (Er) and holmium (Ho) targets with charged particles. This paper reports on the study of the indirect production of 165 Er through the 165 Ho(α,4n) 165 Tm reaction. Holmium foils have been irradiated with a 50 MeV alpha beam, and cross sections for producing 165,166,167,168 Tm were determined using the activation method and stacked target technique, from the threshold to the maximum bombarding energy.

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