What question did this study set out to answer?

To investigate the impact of COVID-19 vaccination during lactation on antibody levels in human milk.

March 30, 2026Journal of Human Lactation0 citations

The COVALAC Study: The Impact of COVID-19 Vaccination During Lactation on SARS-CoV-2-Specific Antibodies in Human Milk—A Prospective Cohort Study

JMJoke MuyldermansVrije Universiteit Brussel SES. EmbacherMedical University of Graz KMKirsten MaertensUniversity of Antwerp

Key Points

To investigate the impact of COVID-19 vaccination during lactation on antibody levels in human milk.
Prospective cohort study design
Assessing SARS-CoV-2-specific antibodies in human milk
Comparing antibody levels post-vaccination
COVID-19 vaccination induces IgA and IgG antibodies in human milk
Higher antibody levels observed after mRNA vaccination than after AVV vaccination
Booster doses further enhance antibody levels.

Abstract

COVID-19 vaccination during lactating induces SARS-CoV-2 specific IgA and IgG antibodies in human milk. Antibody levels were higher following mRNA vaccination compared to AVV vaccination, with booster doses enhancing these levels further.

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