What question did this study set out to answer?

This case report aims to illustrate the rare presentation of juvenile dermatomyositis with transaminitis and the implications of anti-MDA5 positivity.

March 30, 2026JEM ReportsOpen Access

Transaminitis as the Initial Presentation of Anti-MDA5 Positive Juvenile Dermatomyositis: A Case Report

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Authors

MLMirandy Li CBChyna Beck-TaylorMorehouse School of Medicine JCJacinta E. CooperEmory University

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Implication

Case report reveals initial transaminitis in juvenile dermatomyositis, highlighting risk factors and poor prognosis.

Key Points

This case report aims to illustrate the rare presentation of juvenile dermatomyositis with transaminitis and the implications of anti-MDA5 positivity.
Case report of a child with anti-MDA5 positive juvenile dermatomyositis presenting with transaminitis.
Initial misdiagnosis of infective myositis due to lack of classic symptoms.
Follow-up reveal classic JDM symptoms prompting accurate diagnosis.
Patient initially presented with elevated CPK and transaminitis.
Delayed diagnosis due to atypical symptoms led to risk of rapidly progressive ILD.
Early identification of anti-MDA5 positive JDM crucial for prognosis.

Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/69c9c5a4f8fdd13afe0bdac1 https://doi.org/10.1016/j.jemrpt.2026.100239

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Transaminitis as the Initial Presentation of Anti-MDA5 Positive Juvenile Dermatomyositis: A Case Report

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Key Points

Cite This Study

Transaminitis as the Initial Presentation of Anti-MDA5 Positive Juvenile Dermatomyositis: A Case Report

Discussion

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Implication

Key Points

Cite This Study

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