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March 30, 2026Biomaterials Science3 citations

Bioactive Chitosan Scaffolds Reinforced with Hydroxyapatite and Nickel Tungstate for Bone Tissue Engineering

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GGGiovanna de Amorim GrasserDNDiana Gabriela Nina NinaKSKarolyne dos Santos Jorge Sousa

Key Points

  • To improve the performance of bone tissue engineering scaffolds by incorporating bioactive materials.
  • Investigated the mechanical properties of bioactive chitosan scaffolds reinforced with hydroxyapatite and nickel tungstate.
  • Evaluated the scaffolds for controlled ion release and biological activity.
  • Assessed the scaffolds' ability to support bone tissue regeneration.
  • New scaffolds demonstrated enhanced mechanical performance compared to standard BTE scaffolds.
  • Hydroxyapatite incorporation increased biological activity of the scaffolds.
  • Controlled ion release was achieved, promoting better interactions with bone cells.

Abstract

Current bone tissue engineering (BTE) scaffolds often fail to simultaneously provide adequate mechanical performance, controlled ion release, and multifunctional biological activity, particularly when incorporating inorganic antimicrobial agents that may induce...

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Cite This Study

Grasser et al. (2026) studied this question.

synapsesocial.com/papers/69c9c5c5f8fdd13afe0bdb86https://doi.org/10.1039/d6bm00120c
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