Cognitive Function and Oral Health: An Updated Review of the Association with Periodontal Disease and Oral Function, and Future Perspectives

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Key Points

To examine the association between cognitive function and oral health, specifically focusing on periodontal disease and oral function.
Reviewed existing epidemiological studies regarding the relationship between periodontal disease and cognitive decline.
Discussed biological mechanisms, including bacterial invasion and systemic inflammation.
Highlighted the significance of oral diadochokinesis (ODK) related to mild cognitive impairment (MCI).
Identified ODK decline as an independent risk factor for MCI.
Suggested potential for early detection of cognitive decline through changes in oral health.
Emphasized the need for developing self-care strategies tailored to cognitive characteristics.

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This review explores the link between oral health and cognitive function, suggesting implications for dementia prevention.

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Ishihara et al. (2026) studied this question.

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