GABA supplementation combined with home-based exercise improves subjective sleep quality and body composition in elderly women: a randomized trial

March 1, 2026The Journal of Nutritional PhysiologyOpen Access

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Key Points

This study aims to determine if GABA supplementation combined with home-based exercise improves sleep quality and body composition in older women.
Randomized, double-blind, placebo-controlled trial
Participants assigned to 16 weeks of HBEP plus GABA or placebo
Outcomes measured included body composition, handgrip strength, and subjective sleep quality
Dietary intake and metabolic markers were monitored
GABA group exhibited significantly improved PSQI scores (p < 0.001)
GABA group showed greater reduction in body weight (p = 0.006) and BMI (p = 0.002) with increased lean mass (p = 0.003)
Sarcopenia prevalence decreased substantially in the GABA group
Functional performance improved equally in both groups

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Randomized trial shows GABA supplementation improves sleep quality and body composition in elderly women, suggesting practical benefits.

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Trindade et al. (2026) studied this question.

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