Clinical Outcomes of Proton Beam Therapy for Hepatocellular Carcinoma Adjacent to the Gastrointestinal Tract

Yuzheng Zhou; MASAKI NAKAMURA; Kenji Makita; Yuichi Hiroshima; Hidenari Hirata; Toshiya Rachi; HIROMI BABA; Masashi Wakabayashi; MASAFUMI IKEDA; NAOTO GOTOHDA; SADAMOTO ZENDA

doi:10.21873/anticanres.18106

March 27, 2026Anticancer Research

Clinical Outcomes of Proton Beam Therapy for Hepatocellular Carcinoma Adjacent to the Gastrointestinal Tract

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Key Points

Evaluate the effects of proton beam therapy on hepatocellular carcinoma located near the gastrointestinal tract.
Assessed clinical outcomes of patients treated with proton beam therapy for hepatocellular carcinoma
Focused on local recurrence rates and gastrointestinal tract sparing
Comparison of treatment efficacy with and without GI tract sparing
Limited effect on local recurrence rates with GI tract sparing during proton beam therapy
Highlighted the need for more detailed irradiative planning
Potential implications for treatment strategies in similar cases

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Implication

Clinical outcomes reveal limited impact of GI tract sparing during proton beam therapy for hepatocellular carcinoma, indicating a need for further exploration.

Abstract

Sparing the GI tract during PBT for patients with HCC adjacent to the GI tract has a limited effect on LR.

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Cite This Study

Zhou et al. (2026) studied this question.

synapsesocial.com/papers/69ca134b883daed6ee095305 https://doi.org/10.21873/anticanres.18106

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Clinical Outcomes of Proton Beam Therapy for Hepatocellular Carcinoma Adjacent to the Gastrointestinal Tract

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Clinical Outcomes of Proton Beam Therapy for Hepatocellular Carcinoma Adjacent to the Gastrointestinal Tract

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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