Development and validation of the Risk of Exacerbation in Severe Asthma (RESA) model

Wenjia Chen; Tae Yoon Lee; David Price; Richard Beasley; Christer Janson; Mariko Koh Siyue; Chandra Prakash Yadav; Hana Müllerová; Pierre-Regis Burgel; Trung N. Tran; BENJAMIN EMMANUEL; Eileen Wang; Michael E. Wechsler; David J. Jackson; John Busby; Liam G. Heaney; Paul E. Pfeffer; Bassam Mahboub; Diahn-Warng Perng (Steve); Borja G. Cosio; Luis Perez-de-Llano; Riyad Al-Lehebi; Désirée Larenas-Linnemann; Mona Al-Ahmad; Chin Kook Rhee; Takashi Iwanaga; Enrico Heffler; Giorgio Walter Canonica; Richard Costello; Nikolaos G. Papadopoulos; Andriana I. Papaioannou; Celeste Porsbjerg; Carlos A. Torres-Duque; George C. Christoff; Todor A. Popov; Mark Hew; Matthew Peters; Peter G Gibson; Jorge Maspero; Celine Bergeron; Saraid Cerda; Elvia Angelica Contreras; Mohsen Sadatsafavi

doi:10.1016/j.jaip.2026.03.017

March 1, 2026The Journal of Allergy and Clinical Immunology In PracticeOpen Access

Development and validation of the Risk of Exacerbation in Severe Asthma (RESA) model

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Key Points

To develop and validate the Risk of Exacerbation in Severe Asthma (RESA) model for assessing exacerbation risk.
Utilized routinely available predictors to quantify exacerbation risk.
Developed a forecast model for severe asthma exacerbations.
Conducted validation tests to ensure model accuracy.
RESA model effectively quantifies the risk of asthma exacerbations.
Demonstrated potential clinical utility for improved patient management.

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Implication

Model quantifies exacerbation risk in severe asthma, indicating potential clinical use for effective management.

Abstract

The Risk of Exacerbation in Severe Asthma (RESA) model quantifies SA exacerbation risk using routinely available predictors and demonstrates potential clinical utility.

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Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/69cb63c9e6a8c024954b87e4 https://doi.org/10.1016/j.jaip.2026.03.017

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Development and validation of the Risk of Exacerbation in Severe Asthma (RESA) model

Key Points

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Implication

Abstract

Discussion

Cite This Study

Development and validation of the Risk of Exacerbation in Severe Asthma (RESA) model

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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