Should People With a History of Psychosis Be Included in Psychedelic Research?

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Key Points

The aim is to address the exclusion of individuals with a history of psychosis from psychedelic research and the associated ethical concerns.
Reviewed historical context and reasons for exclusion in psychedelic research.
Analyzed clinical and sociocultural implications of exclusion criteria.
Critically engaged with existing literature on psychedelics and psychosis.
Highlighted significant harms due to exclusion, including safety and accessibility issues.
Noted the potential for psychedelics to benefit individuals with negative symptoms of schizophrenia.
Emphasized the need for ethical clinical research that includes individuals with psychosis.

This analysis advocates for including individuals with psychosis in psychedelic research, emphasizing ethical implications and potential benefits.

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Khaleel Rajwani (2026) studied this question.

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