Risk factors for ethambutol-induced optic neuropathy: a systematic review and meta-analysis of comparative studies.

Key Points

• This research aims to identify the risk factors associated with ethambutol-induced optic neuropathy.
• Conducted a systematic review and meta-analysis of comparative studies.
• Analyzed the impact of ethambutol duration, dosage, renal impairment, hypertension, and diabetes.
• Evaluated various studies to derive comprehensive insights.
• Longer duration of ethambutol use is strongly linked to the occurrence of optic neuropathy.
• Renal impairment significantly contributes to the risk of developing this condition.
• The roles of dosage, hypertension, and diabetes require more investigation.