Pre-clinical investigation demonstrates safety of a new eye treatment in rabbits, suggesting shorter testing may be sufficient.
The results of this pre-clinical investigation support the safety and tolerability of the new bacterial-derived OVD in rabbits. There were no statistical differences in IOP and CCT measurements between the two OVDs whether the study endpoints occurred at 7 days or 3 months. Although the study was carried out for 90 days, no statistical differences in clinical performance were observed between OVDs after 7 days, indicating that a testing period that extends out to 90 days may not be medically necessary for pre-clinical studies.
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Moreno et al. (2026) studied this question.
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