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Observational study finds gB2-specific IgG antibodies predict low transmission risk in women, suggesting improved counseling.
In women with a primary CMV infection treated with valacyclovir, the presence of gB2-specific IgG antibodies on immunoblot analysis identifies a subgroup with a low residual risk of maternal-fetal transmission. Incorporating gB2-specific IgG antibodies status into risk stratification may improve patient counseling and clinical decision-making.
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Kagan et al. (2026) studied this question.
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