Case presentation reveals hypocalcemic seizures in siblings due to maternal hyperparathyroidism, indicating importance of thorough medical history.
Late-onset hypocalcemia may be asymptomatic in infants, but the consequences of unrecognized hypocalcemia may lead to seizures and significant morbidity. We present two siblings who developed hypocalcemic seizures early in life due to an undiagnosed maternal parathyroid adenoma, leading to hyperparathyroidism that subsequently required surgery to treat. Had the mother’s medical history been explored earlier, these patients’ acute illness could possibly have been avoided. These cases highlight the importance of a thorough history taking on presentation and identification of the underlying etiology.
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Parker et al. (2026) studied this question.
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