UGT1A1 Fragment Analysis: Genotyping the ( TA ) n Variable Repeat Polymorphism for Clinical Applications

Key Points

• This research focuses on analyzing the UGT1A1 gene polymorphism to enhance clinical pharmacogenomic applications.
• Conducted fragment analysis of UGT1A1 gene
• Included genotyping of the (TA)n variable repeat polymorphism
• Evaluated the assay's effectiveness in clinical settings
• Achieved a correction rate of 7.8% in patient sample genotyping
• 2.77% of miscalls were attributed to the UGT1A1*37 variant