What question did this study set out to answer?

The aim is to explore recent developments in nanotechnologies for precise brain interfacing and neuromodulation.

April 1, 2026Advanced ScienceOpen Access

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

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This review highlights advances in nanomaterials for neuromodulation, suggesting implications for tailored brain therapies.

The aim is to explore recent developments in nanotechnologies for precise brain interfacing and neuromodulation.
Survey of active nanomaterials for neuromodulation
Examination of remotely controlled nanotransducers
Analysis of energy transduction mechanisms
Review of nanosensors for monitoring bioelectrical and neurochemical activity
Discussion on strategies for blood-brain barrier navigation
Identification of nanomaterials enabling precise brain function manipulation
Demonstration of high-resolution monitoring through nanosensors
Evaluation of challenges in translating technologies to clinical applications

Curiale et al. (2026) studied this question.

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