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April 1, 2026SHILAP Revista de lepidopterologíaOpen Access

In vivo efficacy of Zingiber officinale (Zingiberaceae), Punica granatum (Punicaceae), and Foeniculum vulgare (Apiaceae) extracts against Giardia lamblia trophozoites with evaluation of serum IgE levels

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Authors

ADAbdulkarim DakahGAGhassan AbdulrahamanMKMohammed Nour Al Kurdi

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Overview

In vivo study reveals anti-Giardia efficacy of herbal extracts in mice, suggesting new treatment options.

Key Points

  • This research investigates the efficacy of herbal extracts from ginger, pomegranate, and fennel against Giardia lamblia and their effect on serum IgE levels.
  • Prepared ethanolic extracts of ginger, pomegranate, and fennel.
  • Conducted qualitative phytochemical analysis for specific compounds.
  • Inoculated BALB/c mice with Giardia cysts and treated with plant extracts.
  • Measured cyst counts and serum IgE levels at specified intervals.
  • Fennel showed the highest initial cyst reduction (50.8%), followed by ginger (43.9%).
  • At Day 20, metronidazole was most effective (98.1%) followed closely by fennel (90.9%) and ginger (90.5%).
  • Pomegranate extract significantly reduced serum IgE levels by 45%, more than other extracts.

Cite This Study

Dakah et al. (2026) studied this question.

synapsesocial.com/papers/69cd79915652765b073a6736https://doi.org/10.1186/s43088-026-00753-y
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