Traceable gene delivery using minimalistic far red fluorescent pseudodendrimers

Hariharan Moorthy; Pardhasaradhi Satha; Madhu Ramesh; Milind Kumar Anand; T. Govindaraju

doi:10.1039/d6cc00163g

January 1, 2026Chemical Communications

Traceable gene delivery using minimalistic far red fluorescent pseudodendrimers

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Key Points

The study aims to develop a far-red fluorescent pseudodendrimer for efficient and traceable gene delivery.
Developed a minimalistic fluorescent pseudodendrimer platform.
Functionalized the pseudodendrimer with arginine to condense DNA.
Created stable nanocondensates for gene delivery.
The pseudodendrimer effectively delivered DNA.
Nanocondensates formed were stable and traceable.
Demonstrated potential for improved tracking in gene therapy applications.

Implication

This research demonstrates efficient gene delivery using minimalistic pseudodendrimers, indicating promising applications for gene therapy.

Abstract

We report a minimalistic, intrinsically far-red fluorescent pseudodendrimer (PD) platform for efficient and traceable gene delivery. The arginine-functionalized PD (TGP41) condenses DNA to form stable nanocondensates (NCs). When formulated with...

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Cite This Study

Moorthy et al. (2026) studied this question.

synapsesocial.com/papers/69cd7a615652765b073a772c https://doi.org/10.1039/d6cc00163g

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Traceable gene delivery using minimalistic far red fluorescent pseudodendrimers

Key Points

Implication

Abstract

Discussion

Cite This Study

Traceable gene delivery using minimalistic far red fluorescent pseudodendrimers

Key Points

Implication

Abstract

Discussion

Cite This Study

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