Dendrimers with far-red NDI fluorescent core for efficient and traceable gene and RNA delivery

Hariharan Moorthy; Madhu Ramesh; Elumalai Premalatha; T. Govindaraju

doi:10.1039/d5mh01468a

December 5, 2025Materials Horizons

Dendrimers with far-red NDI fluorescent core for efficient and traceable gene and RNA delivery

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Key Points

Dendrimers enhance nucleic acid delivery efficiency, suggesting promise for gene therapy applications.
Key features include increased nucleic acid payload release and improved transfection outcomes.
Observational analysis highlights the advantages of using fluorescent dendrimers for gene and RNA delivery methods.
These findings may enable better therapeutic approaches, calling for further investigation of dendrimer systems.

Implication

Dendrimer-based nucleic acid delivery systems improve transfection efficiency, indicating advanced gene therapy potential.

Abstract

Dendrimer-based nucleic acid (NA) delivery systems have attracted significant attention due to their synthetic versatility, monodispersity, nuclease resistance, high payload release, and transfection efficiency. The conventional dendrimers are non- fluorescent,...

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Cite This Study

Moorthy et al. (2025) studied this question.

synapsesocial.com/papers/694023c82d562116f28fcb18 https://doi.org/10.1039/d5mh01468a

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Dendrimers with far-red NDI fluorescent core for efficient and traceable gene and RNA delivery

Key Points

Implication

Abstract

Discussion

Cite This Study

Dendrimers with far-red NDI fluorescent core for efficient and traceable gene and RNA delivery

Key Points

Implication

Abstract

Discussion

Cite This Study

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