A fluorinated Janus-type dendrimer as an ionizable one-component nanocarrier for nucleic acids

This is the authors' abstract. We don't add key points for this paper.

F-MRI-traceable hydrophobic self-assembling moiety, an optimal balance between fluorinated and hydrophilic groups, and an appropriate number of protonable primary amines. We showed that the designed dendrimer can effectively form dendriplexes with the NAs and safely transport them into different cell types, with successful transfection efficacies and low cytotoxic effects.